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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMEL1
All Species:
15.76
Human Site:
S298
Identified Species:
31.52
UniProt:
Q495T6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q495T6
NP_258428.2
779
89367
S298
D
A
N
L
P
R
D
S
C
L
V
Q
E
D
M
Chimpanzee
Pan troglodytes
XP_001150860
781
89158
S300
D
A
N
L
P
R
D
S
C
L
V
Q
E
D
M
Rhesus Macaque
Macaca mulatta
XP_001105708
750
85452
A270
P
I
D
E
N
Q
L
A
L
E
M
N
K
V
M
Dog
Lupus familis
XP_546737
807
92419
S326
D
M
N
L
P
E
N
S
Y
L
V
R
E
D
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLI3
765
88681
S284
D
Q
N
L
S
K
E
S
A
M
V
R
E
E
M
Rat
Rattus norvegicus
P0C1T0
774
89178
T293
D
L
N
L
P
G
E
T
D
L
V
Q
E
E
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233077
749
86047
Q268
S
K
D
D
L
F
V
Q
E
E
M
A
K
V
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689191
755
86752
E274
D
R
N
L
T
Q
D
E
E
R
V
L
E
D
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511056
849
96515
G371
T
Q
V
A
L
L
L
G
A
D
P
A
T
A
A
Honey Bee
Apis mellifera
XP_392502
776
89056
L298
Y
M
T
N
V
A
V
L
M
G
A
N
R
Q
T
Nematode Worm
Caenorhab. elegans
O16796
848
97043
S368
T
D
G
N
L
T
R
S
E
S
E
M
N
A
D
Sea Urchin
Strong. purpuratus
XP_781407
763
86739
A286
T
I
A
T
L
L
G
A
D
A
Q
V
A
Q
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.9
50.8
82.6
N.A.
77
77.6
N.A.
N.A.
66.2
N.A.
59.9
N.A.
39
40.5
35
38.1
Protein Similarity:
100
97.1
72
89
N.A.
88.6
88.8
N.A.
N.A.
81.6
N.A.
77.6
N.A.
55.9
59.8
54.1
58.5
P-Site Identity:
100
100
6.6
66.6
N.A.
46.6
60
N.A.
N.A.
6.6
N.A.
53.3
N.A.
0
0
6.6
0
P-Site Similarity:
100
100
40
80
N.A.
80
80
N.A.
N.A.
26.6
N.A.
60
N.A.
0
0
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
9
9
0
9
0
17
17
9
9
17
9
17
9
% A
% Cys:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% C
% Asp:
50
9
17
9
0
0
25
0
17
9
0
0
0
34
9
% D
% Glu:
0
0
0
9
0
9
17
9
25
17
9
0
50
17
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
9
9
9
0
9
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
0
9
0
0
0
0
0
0
17
0
0
% K
% Leu:
0
9
0
50
34
17
17
9
9
34
0
9
0
0
0
% L
% Met:
0
17
0
0
0
0
0
0
9
9
17
9
0
0
67
% M
% Asn:
0
0
50
17
9
0
9
0
0
0
0
17
9
0
0
% N
% Pro:
9
0
0
0
34
0
0
0
0
0
9
0
0
0
0
% P
% Gln:
0
17
0
0
0
17
0
9
0
0
9
25
0
17
0
% Q
% Arg:
0
9
0
0
0
17
9
0
0
9
0
17
9
0
0
% R
% Ser:
9
0
0
0
9
0
0
42
0
9
0
0
0
0
9
% S
% Thr:
25
0
9
9
9
9
0
9
0
0
0
0
9
0
9
% T
% Val:
0
0
9
0
9
0
17
0
0
0
50
9
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _